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Organ Preservation Market Overview
Organ Preservation Market size is estimated to reach $337 million by 2027, growing at a CAGR of 6.6% during the forecast period 2022-2027. Organ preservation indicates the supply line for organ transplantation. Presently, the liver, pancreas, and kidney can be favorably preserved for up to two days by flushing the organs with the University of Wisconsin (UW) organ preservation solution and accumulating them at hypothermia (0-5 degree C). Potassium lactobionate is included in organ preservation solutions like Viaspan or CoStorSol that offer osmotic backing and avert cell swelling. Mineral salts of lactobionic acid is also utilized for mineral augmentation. Lactobionic acid is utilized in the cosmetics industry as an antioxidant and in the pharmaceutical industry as an excipient for formulation. For example, the antibiotic erythromycin is applied as the salt erythromycin lactobionate when intravenously transported. Hydroxyethyl starch-based preservation solutions improve gene therapy vector transportation under hypothermic settings. The soaring technological progress is set to drive the Organ Preservation Market. The proliferating count of solid-organ transplantation techniques involving rising antioxidant treatments is set to propel the growth of the Organ Preservation Market during the forecast period 2022-2027. This represents the Organ Preservation Industry Outlook.
Report Coverage
The report: “Organ Preservation
Market Forecast (2022-2027)”, by Industry ARC, covers an in-depth
analysis of the following segments of the Organ Preservation Market.
By
Organ Type: Kidneys, Liver, Lung, Heart,
Others.
By Technique: Static Cold Storage (SCS) Technique, Hypothermic Machine
Perfusion, Normothermic Machine Perfusion and others.
By Geography: North America (the U.S,
Canada, and Mexico), Europe (UK, Germany, France, Italy, Spain, Russia and Rest
of Europe), Asia-Pacific (China, India, Japan, South Korea, Australia & New
Zealand, and Rest of Asia-Pacific), South America (Brazil, Argentina, Rest of
South America) and Rest Of The World (Middle East, Africa).
Key Takeaways
- Geographically, North America Organ Preservation Market accounted for the highest revenue share in 2021 and it is poised to dominate the market over the period 2022-2027 owing to the increasing population of the elderly experiencing heightening incidences of organ failures requiring grafts involving developing antioxidant treatments in the North American region.
- Organ Preservation Market growth is being driven by the boost in government and NGO initiatives to inspire organ donation in conjunction with the burgeoning awareness of organ donations. However, the soaring cost of organ transplantation including antioxidant treatments, a considerable gap between the count of organs donated and organs needed yearly and restricted medical reimbursements for organ donation and transplantation are some of the major factors hampering the growth of Organ Preservation Market.
- Organ Preservation Market Detailed Analysis on the Strength, Weakness, and Opportunities of the prominent players operating in the market will be provided in the Organ Preservation Market report.
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Organ Preservation Market Segment Analysis – By Organ Type:
The Organ Preservation Market
based on organ type can be further segmented into Kidneys, Liver, Lung, Heart and Others. The Kidneys Segment held the
largest market share in 2021. This growth is owing to kidneys being the
most frequently transplanted organs. Corneae and musculoskeletal grafts are the
most routinely transplanted tissues. They surpass organ transplants by beyond
tenfold. There are case reports of hypothermia related with acute renal failure
in patients with diabetic nephropathy and malnutrition. However, in these cases
minimized muscle mass resulting in injured shivering thermogenesis has been
thought to be a significant co-factor adding to hypothermia. The heightening
count of awareness campaigns pertaining to the advantages of kidney transplant
are further propelling the growth of this segment.
Furthermore, the Liver segment is estimated to grow with the fastest
CAGR of 7.1% during the forecast period 2022-2027 owing to the increased
count of cases requiring liver transplant. It has been observed that hypothermia
considerably decreased Malondialdehyde (MDA) in the liver. As per an investigation, individuals
who have a liver transplant have an 89% percent chance of living after one year
and the five-year survival rate is 75 percent. These favorable statistics of
survival rates post liver transplants are further propelling the growth of this
segment.
Organ
Preservation Market Segment Analysis – By Technique:
The Organ Preservation
Market based on technique can be further segmented into Static Cold Storage (SCS) Technique, Hypothermic Machine Perfusion, Normothermic Machine Perfusion, and others.
The Static Cold Storage (SCS) Technique Segment held the largest market share in 2021. This growth is owing to the increased
application of static cold storage (SCS) Technique for
kidney preservation and other organs. Conventional Cold Storage depends on
hypothermia to slow down metabolism and minimize oxygen demand in order to extend
the time of ischemia without accelerated functional graft deterioration, thereby
just delaying graft damage. The existence of different key players providing
static cold storage is further propelling the growth of this segment.
Furthermore, the Normothermic Machine Perfusion segment is estimated to grow with the fastest CAGR of 7.3% during the forecast period 2022-2027 owing to the adequate supply of nutrition and oxygen that allows aerobic metabolism. The superior transplantation results and the minimized chance of post-transplantation side effects together with transplantation techniques employing antioxidant treatments are further fuelling the growth of this segment.
Organ Preservation Market Segment Analysis – By Geography:
The Organ Preservation
Market based on geography can be further segmented into North America, Europe,
Asia-Pacific, South America and Rest of the World. North America (Organ
Preservation Market) held the largest share with 33% of the overall market in
2021. The growth of this region is owing to the supportive
legal foundation commanding organ donation in the U.S. which is built on
principles exclusively planned to back the system of organ transplantation in the region. The presence of
laws like Uniform Anatomical Gift Act (UAGA) is establishing an
agreeable scheme for organ donation and organ transplant which may involve
antioxidant treatments which is propelling the growth of the Organ Preservation
Market in the North American region.
Furthermore, the Asia-Pacific region is estimated to be the region with the fastest CAGR rate over the forecast period 2022-2027. This growth is owing to factors like soaring spend on healthcare, surging patient awareness, and proliferating requirement for organ transplantation techniques which may include antioxidant treatments. The increasing population of the elderly and boost in occurrences of kidney and heart failure are fuelling the progress of the Organ Preservation Market in the Asia-Pacific region.
Organ Preservation Market Drivers
Global
Prevalence Of Incessant Ailments Like Kidney Failure Is
Projected To Drive The Growth Of Organ
Preservation Market:
As per statistics from “The Kidney Project” by University of California San Francisco, almost 750,000 patients per year in the U.S. and an approximate 2 million patients globally endure kidney failure and individuals who accept transplants have a survival rate of around 80% after 5 years. An extended hypothermia may be related with worse renal recovery. In a case of kidney failure, also termed end-stage renal disease (ESRD), either dialysis or a kidney transplant is recommended. Kidney transplant is regarded the most-excellent treatment option for communities enduring kidney failure owing to the boost in opportunity of living a longer, healthier life. Having a kidney transplant may be life-altering for the best. A kidney transplant may be performed when the kidneys are nearing failure, prior to commencing dialysis. Alternatively, dialysis may be initiated while awaiting a kidney transplant. Kidney transplant surgery is deemed secure, and is normally very successful. A successful kidney transplant relies on how healthy the patient is prior to the transplant, taking care of the patient subsequent to transplant, and closely adhering to the instructions of the Doctor consequent to the transplant. The increasing count of cases with kidney failure is fuelling the growth of the Organ Preservation Market during the forecast period 2022-2027.
The Emergence
Of Normothermic Machine Perfusion Is Expected To Boost The Demand Of Organ
Preservation Market:
Kidney transplantation is restricted by preservation techniques based on hypothermia. Extended durations of cold ischaemia boost the hazard of early graft dysfunction and decrease long-term survival. To prolong the borderlines of transplantation and use kidneys from more marginal donors, enhanced techniques of preservation are needed. Normothermic perfusion recovers energy levels in the kidney permitting renal function to be recovered ex vivo. This has numerous benefits like cold ischaemic hurt can be averted or reduced, the kidney can be kept up in a stable state permitting close scrutiny and evaluation of viability and finally, it offers the perfect opportunity to contribute therapies to maneuver in a straightforward manner and enhance the condition of the kidney. The rise of normothermic machine perfusion is driving the growth of the Organ Preservation Market during the forecast period 2022-2027.
Organ Preservation Market Challenges
The Low Count
Of Donors And Crucial Ethical Issues Are Challenging The Organ Preservation
Market:
As per statistics maintained at “The Kidney Project” by University of California San Francisco, over and above 100,000 patients in the U.S are on the kidney transplant list, but in the previous year there were just over 21,000 donor organs readily accessible for transplant and the requirement for donor kidneys in the U.S. is increasing at 8% each year. This great mismatch in the requirement for organ transplants and the donor availability is challenging. A few of the crucial ethical problems that need combative intrusion are organ trafficking, unethical payments for organs, and the delicate balance in live donations between the advantage offered to the recipient and the probable harm to the donor and others. A principal problem in organ transplantation is the definition of death and specifically brain death. These issues are hampering the growth of the Organ Preservation Market.
Organ Preservation Market Landscape:
Product launches, mergers & acquisitions, joint ventures and R&D activities are key strategies adopted by players in the Organ Preservation Market. Key companies of this market include:
- Paragonix Technologies Inc
- 21st Century Medicine Inc.
- Essential Pharmaceuticals LLC
- Organ Recovery Systems, Inc.
- Preservation Solutions, Inc.
- OrganOx
- Transmedics, Inc.
- Waters Medical Systems LLC.
- Xvivo Perfusion AB
- Dr.Franz Kohler Chemie GMBH
Acquisitions/Product Launches:
- In October 2021, Paragonix Technologies, the chief provider of donor organ preservation and transport systems, declared the clinical and commercial introduction of LIVERguard™ Donor Liver Preservation System in U.S. and Europe, together with the kick-off of its clinical global registry, GUARDIAN-LIVER (Global Utilization And Registry Database for Improved preservAtion of doNor LIVERs).
- In August 2021, Paragonix Technologies declared the introduction of its novel OPTION On-Demand Preservation Services Network in the U.S. OPTION is an around-the-clock accelerated deployment service planned to better serve the transplant community and enhance effectiveness in donor organ acquisition and restoration.
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