|pH is a measure
of the acidity or alkalinity of a solution. The acidity or alkalinity of a water solution is determined by the relative number of hydrogen ions (H+) or hydroxyl ions (OH-) present. Conventionally pH is measured through pH sensitive glass electrode, reference electrode or pH meter. Disruptive innovations in sensing techniques have developed the pH sensors which are most reliable inventions to measure the acidity or alkalinity of any solution.
pH sensors are employed in various end user applications which include pulp and paper, medical, food and beverage, agriculture, metal mining and many other end user industries. For several decades, silicon based bio sensors are being used widely in bio technological applications due to favorable characteristics such as sensitivity, speed, and cost effective. In recent times the ion-sensitive field-effect transistor (ISFET), is one of the most popular biosensors, The ISFET, is also referred to as a pH sensor, which is being used to measure ions concentrations (H+ or OH−) in a solution, causing an interface potential on the gate insulator.
ISFET pH sensor is exclusively apt for medical applications. ISFET pH measuring technology is used in FDA and CE approved medical devices. Recent advancements in the field of ISFET biosensors has enabled them to be used in bio-sensing research, including the progress of the enzyme-immobilized FET which detects H+ ion concentration, the DNA modified FET based on DNA hybridization detection, and the cell-based FET for cell metabolism measurement. Currently, the use of ISFET technology covers a wide range of applications in a variety of areas, and those in the biomedical and environmental monitoring areas are particularly remarkable. They are also ideal for food and beverage industrial applications, as they are glass free and can be fitted in probes with a small profile that minimize damage to produce. The increasing applications of these glass free ISFET pH sensors will drive the market for pH sensors
across various end user industries.
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