Programmed self destruction of damaged or abnormal cells is termed as apoptosis. When cells in multicellular organism are no longer required, intracellular destruction of the cells begins. However, excessive and insufficient apoptotic processes have been known to be associated with several diseases. While excessive apoptosis is attributed to atrophy, an insuffienct apoptosis can result in an uncontrolled proliferation of unwanted cells and can result in cancer. There are several other diseases such as neurodegenerative diseases such as Alzeihmer’s, Huntinton’s and ALS and other autoimmune diseases that are stem from either a failure of apoptosis in elimination of harmful cells or unwanted activation of apoptosis that can result in destruction of important cells. Several drugs are available in the market and those currently being research exhibit apoptosis modulating properties.
Rising number of cancer detected patients across the globe is one of the main drivers for the apoptosis market. Research and development efforts by companies as well as universities, sometimes in collaboration, is another factor augmenting the growth of this market. Lack of awareness is one factor that can potentially restrain the growth of this market.
An important section on patent analysis is included in this report that explores some of the most influential patents and potential indications for apoptosis modulation.
The Apoptosis market can be segmented on the basis of mechanism as:
- Bcl-2 Modulators
- Caspase Activators and Inhibitors
- p53 Modulators
- Protease/Proteasome Inhibitors
- Molecular Pathways
The Apoptosis market has also been segmented on the basis of the class of drugs as:
- Direct apoptogens
- First generation indirect apoptogens
- second generation indirect apoptogens
- reagents and kits
One of the main application of apoptosis is for the treatment of cancer.
In terms of type of disease treatment, the Apoptosis market has been segmented across the following diseases:
- Neurodegenerative diseases
- Cardiovascular Diseases
North America currently accounts for the largest share of the global apoptosis market with Europe coming a close second. The market in emerging and developing economies in APAC and South America are expected to grow at higher rates comparatively till the end of the forecast period.
The market has been segmented based on the following geographies:
- North America
- South America
- Middle East
Sample Companies Profiled in this Report are:
- Amgen Inc
- Abbott Laboratories
- Aegera Therapeutics Inc