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Postoperative Pain Market Overview
The Postoperative Pain Market Size is estimated to reach $46.5 billion by 2027 and is poised to grow at a CAGR of 5.0% over the forecast period of 2022-2027. Postoperative pain is a type of acute pain caused by surgical trauma, which causes an inflammatory response and the activation of an afferent neuronal barrage. The market for postoperative pain is seeing explosive growth owing to factors such as rising rates of chronic disease, an increase in surgical procedures, rising awareness of palliative care and rising demand for novel non-opioid analgesics in postoperative pain management therapy. According to National Health data, 100 million procedures are performed in the United States each year. The growing cases of surgeries increase the demand for various drugs for pain management such as paracetamol, opiate, morphine and spinal anesthesia for treatment, thereby driving the postoperative pain management industry. Also, various research and developments by key market players and novel drugs development in the market propel the growth of the postoperative pain industry over the forecast period 2022-2027.
Postoperative Pain Market Report Coverage
The report: “Postoperative Pain Market Forecast (2022-2027)",
by Industry ARC covers an in-depth analysis of the following segments in the Postoperative
Pain Market.
Key Takeaways
- Geographically, North America held a dominant market share in the year 2021, owing to the presence of key market players and high investment in research and development of novel drugs and treatments driving the Postoperative Pain Market size in this region.
- The Postoperative Pain Market is predicted to increase owing to the growing prevalence of chronic diseases and the increasing number of surgeries across the world fuelling the growth of the Postoperative Pain Market.
- A detailed analysis of strengths, weaknesses, opportunities and threats will be provided in the Postoperative Pain Market Report.
Postoperative Pain Market: Market Share (%) by region, 2021
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Postoperative Pain Market Segment Analysis- by Drug
The Postoperative Pain Market based on drugs can be further segmented into NSAIDs, Opioids, Local Anaesthetics, Antiepileptic Drugs, Tricyclic Antidepressants and Others. The opioid segment held a dominant market share in the year 2021. This is owing to the use of opioids or opiates by various routes of administration such as oral, transdermal, parenteral, neuraxial and rectal routes. The most commonly used intravenous opioids for postoperative pain are morphine, paracetamol, hydromorphone (Dilaudid) and fentanyl.
However, NSAIDs are estimated to grow
with the fastest CAGR of 6.1% over the forecast period 2022-2027.
This is owing to the use of nonsteroidal anti-inflammatory drugs for
postoperative pain management. NSAIDs like Naproxen are highly efficient for postoperative pain management.
According to a research paper published in the National Center for
Biotechnology Information in May 2021, found that a single oral dose of 550 mg
of naproxen sodium works well as an analgesic to relieve immediate
postoperative pain.
Postoperative Pain Market Segment Analysis - by Route of Administration
The postoperative Pain Market based on the route of administration can be further segmented into Oral, Injectables, Topical, Transdermal and Others. The Oral segment held a dominant market share in the year 2021. Since oral administration is the most typical method to treat acute or chronic pain various oral opiates such as morphine, hydromorphone, paracetamol, hydrocodone and oxycodone are used. The maximum dose for a single opioid medicine is unrestricted unless the unfavorable consequences of severe sedation or respiratory depression manifest themselves. Such attributes of oral administration and their high preference drive the growth of the Postoperative Pain Market Share.
However, Injectable is estimated to grow
with the fastest CAGR of 5.8% over the forecast period 2022-2027.
This is owing to the quick action of injectable drugs such as spinal
anesthesia for postoperative pain management. Also, injectable drugs provide the
most complete drug availability with minimal delay. Owing to its various
benefits key manufacturers focus on the development of new injectable drugs.
For instance, in August 2022, the U.S. Food and Drug Administration approved
Olinvyk (oliceridine), an opioid agonist, for the treatment of individuals with
moderate to severe acute pain when other treatments are insufficient and the
pain is severe enough to need intravenous opioids.
Postoperative Pain Market Segment Analysis - by Geography
The Postoperative Pain Market based on Geography can be further
segmented into North America, Europe, Asia-Pacific, South America and the Rest
of the World. North America held a dominant market share of 35% in the year
2021. This is the result of the presence of key market players and high
investment in the development of novel therapeutics. For instance, in October
2021, researchers from Duke University and the University of California found a
new drug kenpaullone for chronic pain with the KKC2 gene which is essential for
silencing pain signals. Such growing innovation assists the growth of the Postoperative Pain Market share.
Furthermore, the Asia-Pacific is estimated to grow with the fastest CAGR over the forecast period 2022-2027. This is owing to the growing cases of hospitalization for surgery. According to the Asian Development Bank, near about 645,000 road accident fatalities in Asia and the Pacific every year. Such a high incidence of hospitalization for surgeries and growing cases of accidents in this region surge demand for postoperative pain management and fuel growth of the Postoperative Pain Market share over the forecast period 2022-2027.
Postoperative Pain Market Drivers
Growing Prevalence of Chronic Diseases Enhances Market Expansion.
The increasing prevalence of chronic diseases such
as arthritis or cancer with severe pain increases the demand for pain
management and treatments. According to the World Cancer Research Fund, there were about
18.1 million cancer cases in 2020. A tumor pressing against bones, organs or
nerves can produce pain brought on by cancer. For instance, compression of the
spinal cord, when a tumor penetrates the spine, put pressure on the
spinal cord's nerves which caused pain. To reduce spinal pain the use of spinal
anesthesia is found to be effective in the treatment of severe pain. Such
growing cases of chronic diseases like arthritis and cancer and the need for
pain management treatment fuel the growth of the Postoperative Pain Industry
over the forecast period 2022-2027.
Growing Ambulatory Surgical Centers Enhances Postoperative Pain Market Size.
The growing number of ambulatory surgical centers (ASCs) increases
the growth rate of the Postoperative Pain Market. This is owing to
cost-effective treatment compared to a hospital stay and the convenient service
approach of ambulatory surgical centers. Also, the growing elderly population
increases the demand for ambulatory surgical centers. According to the
Association of Wisconsin Surgery Centers, there are approximately 5,300 ambulatory
surgical centers in the United States and in some states, the number of ASCs
exceeds the number of hospitals. Also, Surgery centers perform around 23
million surgeries annually and the Centers for Medicare & Medicaid Services
(CMS) approves new procedures for the ASC setting every year driving the growth of the Postoperative Pain Industry over the
forecast period 2022-2027.
Postoperative Pain Market Challenge
Adverse
Effects of Medication are Hampering Market Growth
The use of all opioid-based
postoperative pain medications is being restricted in some countries owing to
their severe side effects. According to the CDC, 56,064 persons overdosed on
prescribed opioids in 2021. It is anticipated that rising drug overdose rates
and adverse drug reactions from postoperative pain medications will partially
restrain Postoperative Pain Market expansion over the forecast period
2022-2027.
Postoperative Pain Industry Outlook
Product launches, mergers and acquisitions, joint ventures and
geographical expansions are key strategies adopted by players in the Postoperative
Pain Market. The top 10 companies in the Postoperative Pain Market are:
- Teva Pharmaceutical Industries Ltd.
- Novartis AG
- Allergan plc
- Mylan N.V.
- Pfizer Inc.
- Purdue Pharma L.P.
- Janssen Pharmaceuticals Inc.
- Endo International plc
- Pacira Pharmaceuticals Inc.
- Egalet Corporation
Recent Developments
- In July 2022, Teva Pharmaceuticals, a U.S. affiliate of Teva Pharmaceutical Industries Ltd., announced an agreement with the City and County of San Francisco and the People of the State of California that settles opioid-related claims asserted on behalf of the City of San Francisco.
- In January 2022, Pfizer Inc enters into an agreement with Acuitas Therapeutics for the development of lipid nanoparticle (LNP) delivery systems to enable messenger RNA (mRNA)-based therapeutics. In this development and option agreement, Pfizer has the option to license, on a non-exclusive basis, Acuitas’ LNP technology for up to 10 targets for vaccine or therapeutic development.
- In January 2020, Novartis AG announced the completion of the acquisition of The Medicines Company, through the consummation of a merger of its indirect wholly-owned subsidiary, Medusa Merger Corporation.
Relevant Titles
Report Code: HCR 0120
Report Code: HCR 0197
Report Code: HCR 0116