Ethyl 4-Aminobenzoate Market - Forecast(2024 - 2030)

The Ethyl 4-Aminobenzoate market size is estimated to reach US$20 million, growing at a CAGR of around 4% from 2024 to 2030. The ethyl 4-aminobenzoate, also referred as benzocaine, is an anesthetic that is used in the cough drops and pain relievers. It is soluble in ethanol, ethyl ether, dilute acids and others. The ethyl 4-aminobenzoate has high demand as in pharmaceuticals owing to its medicinal properties and in treatment of various diseases. The high demand of benzocaine or the ethyl 4-aminobenzoate as a pain relief drug component is creating a drive in the Ethyl 4-Aminobenzoate Market. Furthermore, the increasing application of benzocaine in topical anesthetics, dental pain relief and others in pharmaceuticals and cosmetics will offer major growth in the market during the forecast period.

Ethyl 4-Aminobenzoate, is widely used as a local anesthetic in various pharmaceutical products. The trend of increasing demand for pharmaceuticals, coupled with the rising prevalence of minor medical procedures and surgeries, is driving the growth of the Ethyl 4-Aminobenzoate market. Moreover, its applications in over-the-counter products like creams, ointments, and gels for pain relief further contribute to its market expansion.

Despite its widespread use, concerns about the safety profile of Ethyl 4-Aminobenzoate have led to a trend towards seeking safer alternatives, particularly in cosmetic and personal care products. Consumers are becoming more conscious about the ingredients in the products they use, leading manufacturers to explore and invest in the development of substitutes with better safety profiles while maintaining efficacy. This shift is influencing the market dynamics and shaping product development strategies in the Ethyl 4-Aminobenzoate sector.

The global ethyl 4-aminobenzoate industry was majorly impacted by the slowdown due to covid-19 outbreak. The pandemic created major disturbance in production activities, logistics disruptions, and huge gap between the demand and supply chain. The ethyl 4-aminobenzoate has major applications in the pharmaceutical sector. The pharmaceutical or the healthcare industry was majorly affected by the covid-19 disruptions. The raw material supply, manufacturing, and delivery activities were hindered due to restrictions on movement, labor shortages, and others. The demand for drugs, medical supplies, and others was high; however, the supply chain was not fulfilled owing to disruptions in manufacturing activities in the outbreak. According to United States Census Bureau, the revenue of offices of physician and Medical and Diagnostic Laboratories saw a fall of 14.9% and 10.9% respectively in the second quarter of 2020. The decline in growth for the pharmaceutical or healthcare led to major fall in the application of ethyl 4-aminobenzoate in the pharmaceutical sector. Thus, the ethyl 4-aminobenzoate saw a major slowdown in the initial pandemic phase. However, with the recovering healthcare and production activities, the demand for ethyl 4-aminobenzoate will grow post-pandemic.

The report: “Ethyl 4-Aminobenzoate Market Report– Forecast (2024 - 2030)” by IndustryARC covers an in-depth analysis of the following segments of the Ethyl 4-Aminobenzoate industry.

By Purity: Below 98%, 98% and Above 98% 

By Application: Topical Pain Reliever, Earwax Removal, Anesthetic Ointments, Sunscreens, Cough Drops, and Others

By End Use Industry: Pharmaceuticals, Cosmetics, and Others

By Geography: North America (USA, Canada, and Mexico), Europe (UK, Germany, France, Italy, Netherlands, Spain, Russia, Belgium, and Rest of Europe), Asia-Pacific (China, Japan, India, South Korea, Australia, and New Zealand, Indonesia, Taiwan, Malaysia, and Rest of APAC), South America (Brazil, Argentina, Colombia, Chile, and Rest of South America), Rest of the World (Middle East (Saudi Arabia, UAE, Israel, Rest of the Middle East) and Africa (South Africa, Nigeria, Rest of Africa))

• The Ethyl 4-Aminobenzoate Market size will increase owing to its growing application in pharmaceuticals, anesthetic drugs, and high demand in dental treatment during the forecast period.

• The North America region is the fastest growing region in the global ethyl 4-aminobenzoate industry due to rising medical, clinical, and drug production base, along with high demand in treatment of dental pain, skin issues anesthetics, and others.

• The demand for the topical anesthetic products is high in the Ethyl 4-Aminobenzoate Market owing to major use in pain relief from toothache, ulcers, skin irritations, and others.

 

By application, the anesthetic ointment segment accounted for the largest share in the Ethyl 4-Aminobenzoate Market and is expected to grow by around 1.9% during the forecast period 2024 - 2030. The growth of ethyl 4-aminobenzoate or benzocaine for application in anesthetics ointments is rising due to its major use for pain relief and treatment of toothache, sore throats, anal fissure, oral ulcers, and others. According to the India Brand Equity Foundation (IBEF), the Indian Economic Survey 2021 states that the domestic pharmaceutical sector in India is estimated to reach USD 65 billion by 2024 and expanding to reach USD 120-130 billion by 2030. Moreover, the increasing cases of oral ulcers, skin infections and disorders, toothaches, wounds, and others are driving the growth of ethyl 4-aminobenzoate as it is used as a major component in anesthetics in the pharmaceutical sector. Thus, with high demand of ethyl 4-aminobenzoate in drug and medications in pharmaceuticals, the Ethyl 4-Aminobenzoate Market will grow during the forecast period. 

By end-use industry, the pharmaceuticals segment held the largest Ethyl 4-Aminobenzoate Market share and is expected to grow at a CAGR of over 2.1% during the forecast period 2024 - 2030. The ethyl 4-aminobenzoate ha major application in the anesthetics, topical pain reliever, treatment of ulcers, skin disorder, dental irritation, and others. The high demand of ethyl 4-aminobenzoate as a local anesthesia drug in the pharmaceutical sector for surgeries, wounds, and others is propelling the growth in the market. It offers pain relieving and numbing features, thereby boosting its application in the anesthetic drugs, optic pain medications, and orthodontic pain medication. The growth in the pharmaceutical drugs and medication and surgical technologies is offering growth for ethyl 4-aminobenzoate in the market. Thus, with high demand of ethyl 4-aminobenzoate for anesthetic and pain relief medications in pharmaceuticals, the global industry will grow during the forecast period. 

By geography, the North America segment is the fastest-growing region in the Ethyl 4-Aminobenzoate Market and is projected to grow by over 2.6% during the forecast period 2024 - 2030. The growth of ethyl 4-aminobenzoate in this region is influenced by the rising demand of anesthetic for pain relief and surgical procedures. The growth in healthcare sector, advancement in the anesthesia technology, and rising cases of ulcers, dental issues, and geriatric population with chronic complications are factors influencing the demand for ethyl 4-aminobenzoate in this region. Furthermore, the usage of ethyl 4-aminobanzoate for treatment mucosal surfaces, hemorrhoids, narcotic pain, vaginal infection, and others is boosting the growth is propelling the demand in the market. The development in pharmaceutical medications, medical infrastructure, and rising chronic dental and surgical cases is influencing the growth in this region. Thus, with flourishing pharmaceutical and cosmetics sector in North America, the global ethyl 4-aminobenzoate industry will grow during the forecast period.

Rising demand of the anesthetic drugs:

The ethyl 4-aminobenzoate, also known as benzocaine and prepared from ethanol and PABA is a major local anesthesia. The growth of ethyl 4-aminobenzoate is influenced by its rising demand in surgeries and pain relief. It has growing application in pharyngeal and oral mucous membranes such as sore throat, oral ulcers, denture irritation, toothache, and others. Moreover, the growth in surgical procedures and demand of the anesthesia drug or medication is driving the Ethyl 4-Aminobenzoate Market owing to its pain relieving and numbing effects as a local anesthetic. Thus, the growing demand of anesthetic drugs and topical pain-relieving medications is offering major growth opportunities in the market.

The ethyl 4-aminobenzoate has rising demand in the pharmaceutical sector owing to its growing usage in anesthetic drugs, topical pain relief medications, and others. The ethyl 4-aminobezoate or the benzocaine helps in blocking the nerve signals in the body which are responsible for sensing the pain. The topical ethyl 4-aminobenzoate reduces pain and discomfort caused due to sunburn, sore throat, rectal irritation, hemorrhoids, and others. The application of ethyl 4-aminobenzoate in pharmaceutical as a topical ointment, optic pain medication, drug for numbing and pain relief is driving the global ethyl 4-aminobenzoate industry. According to the Department of Pharmaceuticals under the Ministry of Chemicals & Fertilizers and Government of India, India is the 3rd largest market for the API globally with 8% share in the global active pharmaceutical ingredient (API) industry. Thus, the growth and development in pharmaceutical is leading to major demand and growth opportunities in the market.

Severe Health impact and restrictions on use of benzocaine

The ethyl 4-aminobenzote is an air sensitive and light sensitive and gets unstable in contact of strong oxidants, heat, and dust. The toxicity and severe health effects are creating a major challenge on the Ethyl 4-Aminobenzoate Market. The ethyl 4-aminobenzoate creates eye irritation, skin irritation, vomiting, respiratory tract complications, when spilled and not handled carefully. Furthermore, the FDA restricts the use of benzocaine for the treatment of children younger than two years. The restrictions and regulations against the use of benzocaine or ethyl 4-aminobenzoate creates a major growth hindrance on the market, thereby leading to slowdown in the industry.

Technology launches, acquisitions and R&D activities are key strategies adopted by players in the Ethyl 4-Aminobenzoate market. The key companies in the Ethyl 4-Aminobenzoate market are:

1. TCI Chemicals Pvt. Ltd

2. Jinzhou Jiutai Pharmaceutical Co. Ltd

3. Sunlight Pharmaceutical Raw Material Co. Ltd

4. Mahendra Chemicals

5. Thermo Fisher Scientific (Alfa Aesar)

6. Penta International Corporation

7. Pfizer Inc.

8. Valiant (MP Biomedicals)

9. Merck Group (Sigma-Aldrich)

10. Eashu Pharmaceutical

• In October 2023, Pfizer launched Fast-Eze Gel, a new topical gel featuring nano boost technology. Pfizer claimed that it delivers faster pain relief with minimal skin absorption compared to standard gels.

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