Pharmaceuticals Grade Sodium Bicarbonate Market - Forecast(2024 - 2030)

Report Code: CMR 63387 Report Format: PDF + Excel

Pharmaceuticals Grade Sodium Bicarbonate Market Overview

Pharmaceuticals Grade Sodium Bicarbonate market size is forecast to reach US$226.3 million by 2027 after growing at a CAGR of 3.5% during 2022-2027. Sodium bicarbonate (commonly known as baking soda), NaHCO3, is a common ingredient in effervescent tablets and is often used as an acidosis controller. Sodium bicarbonate, of pharmaceutical grade, is used as a pH buffering agent for electrolyte replenishing, as a systemic alkalizer, and in topical cleansing solutions. The demand for pharma-grade sodium bicarbonate has been sparked by factors such as product innovation in light of demographic changes and the expansion of government health programs. The sodium bicarbonate market is expected to grow in tandem with the rapid rise in demand for over-the-counter (OTC) drugs. However, the sodium carbonate market is being hampered by environmental and health concerns, as well as the emergence of substitutes, which are limiting the market growth.

COVID-19 Impact

The pharmaceutical grade sodium bicarbonate was not majorly influenced due to the Covid-19 pandemic scenario. Amidst the pandemic, there was high utilization of sodium bicarbonate in the pharmaceutical industry. There were various research and studies ongoing to understand the incorporation of sodium bicarbonate in coronavirus treatment. For instance, Mansoura University was studying – “The Role of Sodium Bicarbonate as Adjuvant Treatment of Computed Tomography Identified COVID-19 Pneumonia”. Thus, coronavirus did not have any major negative impact on the market growth of the global pharmaceutical grade sodium bicarbonate market. However, there were supply chain disruptions such as raw material delays or non-arrival, disrupted financial flows. As a result, the market remained restrained but production of sodium bicarbonate continued.

Report Coverage

The report: “Pharmaceuticals Grade Sodium Bicarbonate Market – Forecast (2022-2027)”, by IndustryARC, covers an in-depth analysis of the following segments of the Pharmaceuticals Grade Sodium Bicarbonate industry.

By Grade: Fine Grade, Coarse Grade, and Others

By Packaging: Bags, Sacks, and Others

By Application: Active Pharmaceutical Ingredients (API), Excipients, Antacids, Haemodialysis, Tablet Coating, Toothpaste, pH Buffer, and Others

By Geography: North America (USA, Canada, and Mexico), Europe (UK, Germany, France, Italy, Netherlands, Spain, Russia, Belgium, and Rest of Europe), Asia-Pacific (China, Japan, India, South Korea, Australia and New Zealand, Indonesia, Taiwan, Malaysia, and Rest of APAC), South America (Brazil, Argentina, Colombia, Chile, and Rest of South America), Rest of the World (Middle East, and Africa)

Key Takeaways

  • North America dominates the pharmaceuticals grade sodium bicarbonate market, owing to the increasing demand and research activities for pharmaceuticals grade sodium bicarbonate in the region.
  • The growing consumption of sodium-based medicines across the globe owing to the high geriatric population is fueling the demand for pharma grade sodium bicarbonate, thereby driving the market growth. 
  • The pharmaceutical grade sodium bicarbonate, when taken as a supplement by young swimmers, was found to increase their performance by regulating the blood buffering power. Such research activities are presenting various opportunities for pharmaceuticals grade sodium bicarbonate.

Figure: North America Pharmaceuticals Grade Sodium Bicarbonate Market Revenue, 2021-2027 (US$ Million)

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Pharmaceuticals Grade Sodium Bicarbonate Market Segment Analysis – By Application

The active pharmaceutical ingredients (API) segment held the largest share in the pharmaceuticals grade sodium bicarbonate market in 2021 and is forecasted to grow at a CAGR of 3.8% during 2022-2027. Sodium bicarbonate is primarily used as an API and an excipient in the pharma grade sodium bicarbonate market to treat hemodialysis, metabolic acidosis, uncontrolled diabetics, extracorporeal blood circulation, cardiac arrest, and other severe primary lactic acidosis. Sodium bicarbonate is increasingly being used as an active pharmaceutical ingredient in the production of effervescent tablets and as an intermediate in the production of a variety of other pharmaceutical drugs. In the pharmaceutical industry, sodium bicarbonate is used as an active pharmaceutical ingredient to improve drug performance. Increased demand for performing drugs in both established and emerging markets, as well as the need for secondary care small molecules – which are essential in prescription drugs issued by specialists such as oncologists – have all fueled the use of sodium bicarbonate-based active pharmaceutical ingredients in the global pharma industry, according to studies.

Pharmaceuticals Grade Sodium Bicarbonate Market Segment Analysis – By Geography

North America region held the largest share in the pharmaceuticals grade sodium bicarbonate market in 2021 up to 31.2% and is forecasted to grow at a CAGR of 4.5% during 2022-2027. This recent surge can be attributed to the region's growing medical industry, which is catalyzing advanced pharmaceutical trends by taking up new research activities. As a result of this demand for active pharmaceutical ingredients such as sodium bicarbonate is on an upsurge in the region. New drugs have an enormous positive influence on global health, prosperity, and economic productivity by saving lives, increasing life spans, reducing suffering, preventing surgeries, and shortening hospital stays due to which pharmaceutical research and development activities are escalating. According to the Congressional Budget Office report, in the last two decades, both R&D spending and the introduction of new drugs have increased. The pharmaceutical industry spent US$83 billion on research and development in 2019. In comparison to the previous decade, the number of new drugs approved for sale increased by 60% between 2010 and 2019, reaching a high of 59 new drugs approved in 2018. According to the 2019 PMPRB Annual Report, from 2011 to 2019, the value of total pharmaceutical sales (including non-patented over-the-counter medicines) in Canada has increased by 35.3% to US$29.9 billion, with 86.7% sold to retail drug stores and 13.3% sold to hospitals. The European Federation of Pharmaceutical Industries and Associations (EFPIA), in 2019 North America accounted for 48.7% of world pharmaceutical sales compared with 22.9% for Europe. Thus, it is evident from the above statistics that the pharmaceutical industry is flourishing in the region, which is accelerating the demand for pharmaceuticals grade sodium bicarbonate in North America during the forecast period.

Pharmaceuticals Grade Sodium Bicarbonate Market Drivers

Increasing Research and Development Activities

There are increasing research and development activities to unlatch new applications of pharmaceuticals grade sodium bicarbonate. Giving pharma-grade sodium bicarbonate to women in labor increased their chances of having a natural, vaginal delivery, according to researchers from the University of Liverpool and the Karolinska Institute in Sweden. A group of women was given pharma grade sodium bicarbonate in addition to oxytocin, while another group was given only oxytocin – a drug that helps strengthen contractions. Bicarbonate of soda consumption increased the chances of vaginal delivery by 17 percent when compared to only administering oxytocin, which only helped in a few cases, leaving emergency caesarean section as the only option in the remaining cases. This type of therapeutic use of pharma grade sodium bicarbonate, according to researchers, will reduce Amniotic Fluid Lactate (AFL) levels, which are usually associated with operative interventions. Such kinds of research and developments activities are anticipated to unlatch new applications for pharmaceuticals grade sodium bicarbonate market, thereby driving the market growth.

Flourishing Pharmaceutical Sector

In developing countries with a thriving pharmaceutical sector, low-cost treatments using pharma grade sodium bicarbonate have the potential to improve mortality rates. The global market for pharma-grade sodium bicarbonate therapeutics is expected to benefit from this. According to the European Federation of Pharmaceutical Industries and Associations (EFPIA), during the period 2014-2019 the Brazilian, Chinese and Indian markets grew by 11.2%, 6.9%, and 11.1% respectively compared to average market growth of 5.4% for the top 5 European Union markets and 6.1% for the US market. According to Invest India, The pharmaceutical industry in India is expected to reach US$65 billion by 2024 and US$120 billion by 2030. Due to this increase in the pharmaceutical industry, the pharmaceuticals grade sodium bicarbonate market is expected to exhibit rapid growth over the forecast period. Furthermore, favorable government policies, such as those relating to foreign direct investments, healthcare facilities, and infrastructure development programs like cluster development in the pharmaceuticals sector, are expected to drive revenue growth in the global pharma grade sodium bicarbonate market.

Pharmaceuticals Grade Sodium Bicarbonate Market Challenges

Availability of Low-Cost Alternatives

Calcium carbonate, calcium chloride, and other sodium bicarbonate substitutes are used in pharmaceutical applications. Limestone, chalk, marble, calcite, seashells, and corals are all examples of calcium carbonate in nature. Sodium bicarbonate is a stronger base than calcium carbonate, even though calcium carbonate is a soluble alkali. The sodium bicarbonate salt is relatively inexpensive, and excessive consumption of sodium source compounds can lead to kidney disease and high blood pressure, which can lead to heart failure or stroke. Calcium carbonate is a better and safer alternative to sodium bicarbonate as a first-line treatment for heartburn. Calcium carbonate is an over-the-counter remedy that works in seconds. Calcium chloride is available in chewable form and has few side effects. Thus, such low-cost alternatives of pharmaceuticals grade sodium bicarbonate are posing a significant challenge for the pharmaceuticals grade sodium bicarbonate market.

Pharmaceuticals Grade Sodium Bicarbonate Industry Outlook

Technology launches, acquisitions, and R&D activities are key strategies adopted by players in the Pharmaceuticals Grade Sodium Bicarbonate market. Pharmaceuticals Grade Sodium Bicarbonate market top companies are:

  1. Tata Chemicals
  2. Novacarb (Novacap Group)
  3. Dr. Paul Lohmann GmbH KG
  4. GHCL Limited
  5. CIECH S.A.
  6. Natural Soda LLC
  7. Jost Chemical Co.
  8. Tronox Alkali Corporation
  9. EXELA Pharma Sciences, LLC
  10. Solvay SA

Recent Developments

  • In September 2019, Exela Pharma Sciences launched Sodium Bicarbonate Injection, USP. Exela's ANDA for Sodium Bicarbonate Injection was approved in May for four different presentations. The first is an injection of 8.4% sodium bicarbonate in 50mEq/50mL (1mEq/mL) vials. This product has consistently been on the FDA Drug Shortage List, and it is the only FDA-approved Sodium Bicarbonate Injection on the market in the United States.

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1. Pharmaceuticals Grade Sodium Bicarbonate Market- Market Overview
    1.1 Definitions and Scope
2. Pharmaceuticals Grade Sodium Bicarbonate Market- Executive Summary
    2.1 Key Trends by Grade
    2.2 Key Trends by Packaging
    2.3 Key Trends by Application
    2.4 Key Trends by Geography
3. Pharmaceuticals Grade Sodium Bicarbonate Market – Comparative analysis
    3.1 Market Share Analysis- Major Companies
    3.2 Product Benchmarking- Major Companies
    3.3 Top 5 Financials Analysis
    3.4 Patent Analysis- Major Companies
    3.5 Pricing Analysis (ASPs will be provided)
4. Pharmaceuticals Grade Sodium Bicarbonate Market - Startup companies Scenario Premium Premium
    4.1 Major startup company analysis:
        4.1.1 Investment
        4.1.2 Revenue
        4.1.3 Product portfolio
        4.1.4 Venture Capital and Funding Scenario
5. Pharmaceuticals Grade Sodium Bicarbonate Market – Industry Market Entry Scenario Premium Premium
    5.1 Regulatory Framework Overview
    5.2 New Business and Ease of Doing Business Index
    5.3 Successful Venture Profiles
    5.4 Customer Analysis – Major companies
6. Pharmaceuticals Grade Sodium Bicarbonate Market - Market Forces
    6.1 Market Drivers
    6.2 Market Constraints
    6.3 Porters Five Force Model
        6.3.1 Bargaining Power of Suppliers
        6.3.2 Bargaining Powers of Buyers
        6.3.3 Threat of New Entrants
        6.3.4 Competitive Rivalry
        6.3.5 Threat of Substitutes
7. Pharmaceuticals Grade Sodium Bicarbonate Market – Strategic Analysis
    7.1 Value Chain Analysis
    7.2 Opportunity Analysis
    7.3 Product/Market Life Cycle
    7.4 Distributor Analysis – Major Companies
8. Pharmaceuticals Grade Sodium Bicarbonate Market - By Grade (Market Size -US$ Million/Billion)
        8.1.1 Fine Grade
        8.1.2 Coarse Grade
        8.1.3 Others
9. Pharmaceuticals Grade Sodium Bicarbonate Market - By Packaging (Market Size -US$ Million/Billion)
        9.1.1 Bags
        9.1.2 Sacks
        9.1.3 Others
10. Pharmaceuticals Grade Sodium Bicarbonate Market - By Application (Market Size -US$ Million/Billion)
    10.1 Active Pharmaceutical Ingredients (API)
    10.2 Excipients
    10.3 Antacids
    10.4 Haemodialysis
    10.5 Tablet Coating
    10.6 Toothpaste
    10.7 pH Buffer
    10.8 Others
11. Pharmaceuticals Grade Sodium Bicarbonate Market - By Geography (Market Size -US$ Million/Billion)
    11.1 North America
        11.1.1 USA
        11.1.2 Canada
        11.1.3 Mexico
    11.2 Europe
        11.2.1 UK
        11.2.2 Germany
        11.2.3 France
        11.2.4 Italy
        11.2.5 Netherlands
        11.2.6 Spain
        11.2.7 Russia
        11.2.8 Belgium
        11.2.9 Rest of Europe
    11.3 Asia-Pacific
        11.3.1 China
        11.3.2 Japan
        11.3.3 India
        11.3.4 South Korea
        11.3.5 Australia and New Zealand
        11.3.6 Indonesia
        11.3.7 Taiwan
        11.3.8 Malaysia
        11.3.9 Rest of APAC
    11.4 South America
        11.4.1 Brazil
        11.4.2 Argentina
        11.4.3 Colombia
        11.4.4 Chile
        11.4.5 Rest of South America
    11.5 Rest of the World
        11.5.1 Middle East
            11.5.1.1 Saudi Arabia
            11.5.1.2 UAE
            11.5.1.3 Israel
            11.5.1.4 Rest of the Middle East
        11.5.2 Africa
            11.5.2.1 South Africa
            11.5.2.2 Nigeria
            11.5.2.3 Rest of Africa
12. Pharmaceuticals Grade Sodium Bicarbonate Market – Entropy
    12.1 New Product Launches
    12.2 M&As, Collaborations, JVs and Partnerships
13. Pharmaceuticals Grade Sodium Bicarbonate Market – Market Share Analysis Premium
    13.1 Company Benchmarking Matrix – Major Companies
    13.2 Market Share at Global Level - Major companies
    13.3 Market Share by Key Region - Major companies
    13.4 Market Share by Key Country - Major companies
    13.5 Market Share by Key Application - Major companies
    13.6 Market Share by Key Product Type/Product category - Major companies
14. Pharmaceuticals Grade Sodium Bicarbonate Market – Key Company List by Country Premium Premium
15. Pharmaceuticals Grade Sodium Bicarbonate Market Company Analysis - Business Overview, Product Portfolio, Financials, and Developments
    15.1 Company 1
    15.2 Company 2
    15.3 Company 3
    15.4 Company 4
    15.5 Company 5
    15.6 Company 6
    15.7 Company 7
    15.8 Company 8
    15.9 Company 9
    15.10 Company 10 and more
"*Financials would be provided on a best efforts basis for private companies"