Protein Purification & Isolation Market - Forecast(2024 - 2030)

Protein Purification & Isolation Market Overview

Protein Purification & Isolation Market Size is estimated to reach $7.8 billion by 2027. It is poised to grow at a CAGR of 8.3% over the forecast period of 2022-2027. Protein Purification and Isolation are procedures in which proteins are extracted from a complex mixture that is made up of cells or tissues. Protein purification and separation have been achieved using ion exchange chromatography. Protein purification and separation technologies are effectively used in applications such as drug screening, affinity chromatography, gel electrophoresis, biomarker discovery, protein therapeutics, target identification and others. The increasing research areas in biotechnology for the development of innovative drugs and the growing research and development activities for developing protein purification & isolation technologies are contributing to the growth of the Protein Purification & Isolation Market for the forecast period 2022-2027. 

Protein Purification & Isolation Market Report Coverage

The report: “Protein Purification & Isolation Market Forecast (2022-2027)" by IndustryARC covers an in-depth analysis of the following segments of the Protein Purification & Isolation Market.

Key Takeaways

• Geographically, North America held a dominant market share in the year 2021, owing to the growing demand for drug screening and protein therapeutics. In addition, the companies are focusing on developing advanced protein isolation technologies. A robust economy and a growing trend in healthcare facilities are driving demand for Protein Purification & Isolation Market in this region.
• The increasing adoption of ion exchange for separating proteins in a solution is driving the growth of the Protein Purification & Isolation Market. However, the high cost of protein purification & isolation kits is expected to hinder the growth of the target market to a certain extent. 
• A detailed analysis of strengths, weaknesses, opportunities and threats will be provided in the Protein Purification & Isolation Market Report.

Protein Purification & Isolation Market Segmentation Analysis- By Application

Protein Purification & Isolation Market based on the application can be further segmented into Drug Screening, Affinity Chromatography, Gel Electrophoresis, Biomarker Discovery, Protein Therapeutics, Target Identification and Others. Drug Screening held a dominant market share in the year 2021. The rise in the demand for identifying potential drugs to optimize before the selection of a candidate drug to progress to clinical trials is propelling the demand for drug screening. The key players are focusing on developing advanced protein purification & isolation technologies for drug screening.

However, Protein Therapeutics is estimated to be the fastest-growing, with a CAGR of 9.2% over the forecast period of 2022-2027. Protein Therapeutics is used to replace a protein that is abnormal or deficient in a specific disease. They can also supplement the supply of a beneficial protein, which can help mitigate the effects of disease or chemotherapy.

Protein Purification & Isolation Market Segmentation Analysis- By End Use

Protein Purification & Isolation Market based on the End-Use can be further segmented into Academic and Research Institutes, Pharmaceutical and Biotechnology Companies, Hospitals and Diagnostic Centers and Others. The Academic and Research Institutes segment held a dominant market share in the year 2021. The rise in the demand for drug screening; ion exchange methods in academic and research institutes; and the growing availability of advanced technologies for protein purification and isolation are the major factors contributing to the growth of the Protein Purification & Isolation Market.

However, the Pharmaceutical and Biotechnology Companies segment is estimated to be the fastest-growing, with a CAGR of 9.0% over the forecast period of 2022-2027. Pharmaceutical and Biotechnology Companies are effectively using affinity chromatography and gel electrophoresis. As a result, the market for Protein Purification & Isolation is expected to grow throughout the forecast period.

Protein Purification & Isolation Market Segmentation Analysis- By Geography

The Protein Purification & Isolation Market based on Geography can be further segmented into North America, Europe, Asia-Pacific, South America and the Rest of the World. North America held a dominant market share of 36% in the year 2021. The rise in the adoption of drug screening methods in the region is driving the growth of the market. Key manufacturers are leading the Protein Purification & Isolation market in this region with innovative protein purification and isolation technologies.

Furthermore, Asia-Pacific is estimated to grow with the fastest CAGR over the forecast period 2022-2027. The development of healthcare infrastructure in the region and an increase in the support from the governments by providing funds for the development of novel drugs are the major factors driving the growth of the Protein Purification & Isolation market.

Protein Purification & Isolation Market Drivers

Increase in the Demand for Drug Screening is a Key Factor for Market Growth.

According to the National Safety Council 2020 Statistics, 18% of Americans reported using an illicit drug in the past year and 4.2% of employees in the U.S. workforce failed a drug test. This rise in the prevalence of drug problems is enhancing the implementation of drug screening programs across the world. Modern drug screening utilizes libraries of purified proteins that are screened by libraries of small molecule drug precursors and greatly speeds up the identification of new drug molecules; which is one of the major factors driving the growth of the Protein Purification & Isolation Market.

The Rise in the Adoption of Affinity chromatography is Propelling the Market Growth.

According to the National Center for Biotechnology Information (NCBI), Affinity chromatography is involved in more than 60% of all purification techniques in 2020 and it depends on a molecule bound to a column to recognize the target molecule. In Affinity chromatography, the protein of interest is purified by virtue of its specific binding properties to an immobilized ligand. Moreover, Affinity chromatography relies on the specific and reversible binding of a protein to a matrix-bound ligand.

Protein Purification & Isolation Market Challenges 

High Cost of Protein Purification & Isolation Kits is Hampering the Growth of the Protein Purification & Isolation Market.

The price of Protein Purification & Isolation Kits is around $450-$2,000. The growing demand for advanced instruments and reagents that provides fast, dependable and reproducible protein purification at a modest cost, is further increasing the price of these kits and making it difficult for the start-up companies to enter the market; which is one of the major factors that is said to reduce the growth of the Protein Purification & Isolation Market.

Protein Purification & Isolation Industry Outlook

Product launches, mergers & acquisitions, joint ventures and geographical expansions are key strategies adopted by players in the Protein Purification & Isolation Market. Top 10 companies in the Protein Purification & Isolation Market are:

1. Thermo Fisher Scientific
2. QIAGEN N.V
3. Purolite
4. Agilent Technologies
5. Promega Corporation
6. Norgen Biotek Corporation
7. GE Healthcare Life Sciences
8. Sigma-Aldrich Corporation
9. Bio-Rad Laboratories
10. Roche Applied Science

Recent Developments

• In January 2022, QIAGEN N.V. launched QIAwave product line by launching three nucleic acid extraction kits that use fewer components. These products are designed in collaboration with customers to tackle the persistent problem of laboratory waste faced by scientists all over the world. These technologies isolate and process DNA, RNA and proteins from blood, tissues and other types.
• In October 2021, Purolite, a manufacturer of resin-based chromatography separation has launched two next-generation chromatography resins. Praesto Jetted A50 HipH is the world's first protein. It’s an alkaline stable resin based on a 50m uniform agarose bead. It is designed to address the purification of pH-sensitive antibodies or other Fc-containing proteins.
• In April 2021, Thermo Fisher Scientific has launched the KingFisher Apex Purification System. It is a high-throughput sample purification instrument that is designed for scientists who need to automate the extraction of DNA, proteins and cells from an array of sample types. The KingFisher Apex purification system enables protein and cell isolation while allowing users to customize protocols.

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