Cell Dissociation Market – By Method, By Product, By Application, By End User, By Geography - Global Opportunity Analysis & Industry Forecast, 2024-2030
Cell Dissociation Market Overview
Cell Dissociation Market is forecast to reach $1.7 billion by 2030, after growing at a CAGR of 16.3% during 2024-2030. Growing demand for cell therapy, increasing investment in cell-based research & growth of pharmaceutical & biotechnological industries are the major drivers for the cell dissociation market, as increased investment in biotechnology and life sciences fuels demand for advanced cell dissociation techniques. The expansion of research in areas such as stem cell biology, cancer studies and regenerative medicine necessitates efficient and reliable cell dissociation methods for isolating and manipulating cells. This surge in R&D activities not only drives innovation in dissociation technologies but also supports the development of new applications and therapies, further propelling market growth.
One of the most significant trends in cell dissociation is the growing use of single-cell RNA sequencing (scRNA-seq) techniques. For effective scRNA-seq, high-quality cell dissociation is critical to ensure the integrity of individual cells. This method is increasingly important in drug discovery enabling scientists to identify unique cellular responses to drugs, uncover rare cell populations and develop more targeted therapies. Artificial intelligence is emerging as a transformative trend in cell dissociation processes particularly in optimizing protocols and improving cell viability. For instance, in October 2023, Molecular Devices, LLC. launched the patent-pending CellXpress.ai Automated Cell Culture System—an end-to-end, machine learning-enabled solution. By leveraging the power of automation and artificial intelligence, the CellXpress.ai cell culture system empowers researchers to achieve reliable, reproducible, and biologically relevant results at scale while streamlining routine responsibilities. AI-driven tools can analyze large datasets to predict the best dissociation methods for specific cell types reducing the time required for trial and error.
Market Snapshot:
Cell Dissociation Market – Report Coverage
The report: “Cell Dissociation Market – Forecast (2024-2030)”, by IndustryARC, covers an in-depth analysis of the following segments of the Cell Dissociation Market.
Attribute | Segment |
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By Method |
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By Product |
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By Application |
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By End User |
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By Geography |
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COVID-19 / Ukraine Crisis - Impact Analysis:
- COVID highlighted the importance of cell-based research for understanding and combating diseases driving increased interest in developing efficient and reliable cell dissociation techniques. According to an article published in the National Library of Medicine in December 2020, cell isolation was used to diagnose and assess treatments for COVID-19.
- The Russia-Ukraine conflict impacted the cell dissociation market indirectly. Due to countries boosting their military spending reducing the spending on funding for the science and healthcare sector particularly towards research.
Key Takeaways
Enzymatic Dissociation Hold the Largest Share
Enzymatic dissociation is the most widely used technology in the cell dissociation market due to its effectiveness in breaking down extracellular matrices and cellular adhesions. It is versatile suitable for both adherent and suspension cells and well-established in research and clinical settings. This method's compatibility with downstream applications and its efficiency in handling large sample volumes contribute to its widespread adoption. While mechanical, chemical and automated systems are also used, enzymatic dissociation remains the preferred choice due to its proven reliability and broad applicability.
Stem Cell Research is the Largest Segment
Stem cell research represents the largest application of cell dissociation driven by the need for precise isolation and culture of these cells for therapeutic and research purposes. Tissues such as bone marrow and adipose tissue are primary sources of Mesenchymal Stem Cells (MSCs) and Hematopoietic Stem Cells (HSCs), which are pivotal for regenerative medicine, transplantation and tissue engineering. Stem cells, especially pluripotent and mesenchymal stem cells, require dissociation techniques that maintain their viability and differentiation potential. Researchers utilize cell dissociation to efficiently isolate and expand stem cells, enabling advancements in personalized medicine, gene therapy and tissue regeneration. The global focus on developing stem cell therapies to treat a range of diseases has significantly increased the demand for high-quality dissociation methods, making this the largest application area. For instance, in September 2024, the Australian Government announced an investment $34.5 million in research funding to trial new treatments and therapies to utilize the power of stem cells to improve patient outcomes.
North America Dominates the Market
North America holds the largest market share in the cell dissociation market mainly due to the high incidence of cancer and other chronic diseases in the region. The rising prevalence of diseases such as cancer, diabetes, and cardiovascular disorders has driven significant investments in cell-based research, particularly in the areas of stem cell therapy and drug discovery. In September 2023, the White House announced a $240 million investment to fight cancer, the money will go to researchers working on cancer prevention, detection, treatment and survival projects. These chronic diseases necessitate advanced research and personalized treatment approaches for which cell dissociation plays a critical role in isolating viable cells for study. Furthermore, the strong presence of leading biotech and pharmaceutical companies in the U.S. and Canada amplify research spending accelerating the development of innovative cell-based therapies and contributing to the regions dominant market position.
Growth in Cell Based Therapy Research
Advancements in research and development are refining techniques and expanding the applications of cell dissociation. The increased use of cell-based therapies and personalized medicine drives the need for more effective dissociation methods. Technological progress, such as automation and integration with omics technologies, boosts process efficiency. Growing investment and funding foster innovation, while the expansion of research fields further propels market growth. Collectively, these factors support the continuous evolution and broadening scope of cell dissociation technologies in both scientific and clinical contexts. According to the American Society of Cell and Gene Therapy, in Q1 2024, the cell and gene therapy field experienced notable growth, with over 4,000 gene, cell and RNA therapies currently in development. There was a significant 11% increase in Phase I clinical programs reflecting heightened research activity.
Cell Viability and Quality to Hamper the Market
Cell viability and quality present a major challenge in cell dissociation. Ensuring that cells remain alive and functional after dissociation is crucial for accurate research and effective therapies. The process can expose cells to damage from mechanical and enzymatic stress potentially affecting their integrity and functionality. Consistency in cell quality across different dissociation methods is difficult to achieve and preserving specific cellular characteristics requires rigorous quality control which can be complex and costly. Overall, maintaining high cell viability and quality is essential for reliable outcomes in various applications. According to Danaher, stress factors such as mechanical forces, radiation, chemical changes and temperature fluctuations can impact cells, potentially causing differentiation, reduced viability, stress responses or apoptosis. Ensuring cell viability and identity is crucial during single-cell isolation for monoclonal cultures or stem cell studies.
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Cell Dissociation Market Key Players
Product/Service launches, approvals, patents and events, acquisitions, partnerships and collaborations are key strategies adopted by players in the Cell Dissociation Market.
The top 10 players in the Cell Dissociation market are
- Thermo Fisher Scientific
- Corning Incorporated
- BD
- F Hoffmann-La Roche Ltd
- GE Healthcare
- Himedia Laboratory
- Merck KGaA
- Miltenyi Biotec
- Sartorius AG
- Danaher Corporation
Scope of the Report:
Report Metric | Details |
---|---|
Base Year Considered |
2023 |
Forecast Period |
2024–2030 |
CAGR |
16.3% |
Market Size in 2030 |
$1.7 Billion |
Segments Covered |
By Method, By Product, By Application, By End User and By Geography. |
Geographies Covered |
North America (U.S., Canada and Mexico), Europe (Germany, France, UK, Italy, Spain, Netherlands, Belgium and Rest of Europe), Asia-Pacific (China, Japan, South Korea, India, Australia, Indonesia, Malaysia and Rest of Asia-Pacific), South America (Brazil, Argentina, Chile, Colombia and Rest of South America) and Rest of the World (Middle East and Africa). |
Key Market Players |
1. Thermo Fisher Scientific 2. Corning Incorporated 3. BD 4. F Hoffmann-La Roche Ltd 5. GE Healthcare 6. Himedia Laboratory 7. Merck KGaA 8. Miltenyi Biotec 9. Sartorius AG 10. Danaher Corporation |
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LIST OF TABLES
1.Global Cell Dissociation Market, By Product Market 2023-2030 ($M)
1.1 Enzymatic Dissociation Product Market 2023-2030 ($M) - Global Industry Research
1.1.1 Collagenase Market 2023-2030 ($M)
1.1.2 Trypsin Market 2023-2030 ($M)
1.1.3 Papain Market 2023-2030 ($M)
1.1.4 Elastase Market 2023-2030 ($M)
1.1.5 Dnase Market 2023-2030 ($M)
1.1.6 Hyaluronidase Market 2023-2030 ($M)
1.2 Non-Enzymatic Dissociation Product Market 2023-2030 ($M) - Global Industry Research
1.3 Instrument & Accessory Market 2023-2030 ($M) - Global Industry Research
2.Global Cell Dissociation Market, By Tissue Market 2023-2030 ($M)
2.1 Connective Tissue Market 2023-2030 ($M) - Global Industry Research
2.2 Epithelial Tissue Market 2023-2030 ($M) - Global Industry Research
3.Global Cell Dissociation Market, By Type Market 2023-2030 ($M)
3.1 Tissue Dissociation Market 2023-2030 ($M) - Global Industry Research
3.2 Cell Detachment Market 2023-2030 ($M) - Global Industry Research
4.Global Cell Dissociation Market, By End User Market 2023-2030 ($M)
4.1 Pharmaceutical & Biotechnology Company Market 2023-2030 ($M) - Global Industry Research
4.2 Research & Academic Institute Market 2023-2030 ($M) - Global Industry Research
5.Global Cell Dissociation Market, By Product Market 2023-2030 (Volume/Units)
5.1 Enzymatic Dissociation Product Market 2023-2030 (Volume/Units) - Global Industry Research
5.1.1 Collagenase Market 2023-2030 (Volume/Units)
5.1.2 Trypsin Market 2023-2030 (Volume/Units)
5.1.3 Papain Market 2023-2030 (Volume/Units)
5.1.4 Elastase Market 2023-2030 (Volume/Units)
5.1.5 Dnase Market 2023-2030 (Volume/Units)
5.1.6 Hyaluronidase Market 2023-2030 (Volume/Units)
5.2 Non-Enzymatic Dissociation Product Market 2023-2030 (Volume/Units) - Global Industry Research
5.3 Instrument & Accessory Market 2023-2030 (Volume/Units) - Global Industry Research
6.Global Cell Dissociation Market, By Tissue Market 2023-2030 (Volume/Units)
6.1 Connective Tissue Market 2023-2030 (Volume/Units) - Global Industry Research
6.2 Epithelial Tissue Market 2023-2030 (Volume/Units) - Global Industry Research
7.Global Cell Dissociation Market, By Type Market 2023-2030 (Volume/Units)
7.1 Tissue Dissociation Market 2023-2030 (Volume/Units) - Global Industry Research
7.2 Cell Detachment Market 2023-2030 (Volume/Units) - Global Industry Research
8.Global Cell Dissociation Market, By End User Market 2023-2030 (Volume/Units)
8.1 Pharmaceutical & Biotechnology Company Market 2023-2030 (Volume/Units) - Global Industry Research
8.2 Research & Academic Institute Market 2023-2030 (Volume/Units) - Global Industry Research
9.North America Cell Dissociation Market, By Product Market 2023-2030 ($M)
9.1 Enzymatic Dissociation Product Market 2023-2030 ($M) - Regional Industry Research
9.1.1 Collagenase Market 2023-2030 ($M)
9.1.2 Trypsin Market 2023-2030 ($M)
9.1.3 Papain Market 2023-2030 ($M)
9.1.4 Elastase Market 2023-2030 ($M)
9.1.5 Dnase Market 2023-2030 ($M)
9.1.6 Hyaluronidase Market 2023-2030 ($M)
9.2 Non-Enzymatic Dissociation Product Market 2023-2030 ($M) - Regional Industry Research
9.3 Instrument & Accessory Market 2023-2030 ($M) - Regional Industry Research
10.North America Cell Dissociation Market, By Tissue Market 2023-2030 ($M)
10.1 Connective Tissue Market 2023-2030 ($M) - Regional Industry Research
10.2 Epithelial Tissue Market 2023-2030 ($M) - Regional Industry Research
11.North America Cell Dissociation Market, By Type Market 2023-2030 ($M)
11.1 Tissue Dissociation Market 2023-2030 ($M) - Regional Industry Research
11.2 Cell Detachment Market 2023-2030 ($M) - Regional Industry Research
12.North America Cell Dissociation Market, By End User Market 2023-2030 ($M)
12.1 Pharmaceutical & Biotechnology Company Market 2023-2030 ($M) - Regional Industry Research
12.2 Research & Academic Institute Market 2023-2030 ($M) - Regional Industry Research
13.South America Cell Dissociation Market, By Product Market 2023-2030 ($M)
13.1 Enzymatic Dissociation Product Market 2023-2030 ($M) - Regional Industry Research
13.1.1 Collagenase Market 2023-2030 ($M)
13.1.2 Trypsin Market 2023-2030 ($M)
13.1.3 Papain Market 2023-2030 ($M)
13.1.4 Elastase Market 2023-2030 ($M)
13.1.5 Dnase Market 2023-2030 ($M)
13.1.6 Hyaluronidase Market 2023-2030 ($M)
13.2 Non-Enzymatic Dissociation Product Market 2023-2030 ($M) - Regional Industry Research
13.3 Instrument & Accessory Market 2023-2030 ($M) - Regional Industry Research
14.South America Cell Dissociation Market, By Tissue Market 2023-2030 ($M)
14.1 Connective Tissue Market 2023-2030 ($M) - Regional Industry Research
14.2 Epithelial Tissue Market 2023-2030 ($M) - Regional Industry Research
15.South America Cell Dissociation Market, By Type Market 2023-2030 ($M)
15.1 Tissue Dissociation Market 2023-2030 ($M) - Regional Industry Research
15.2 Cell Detachment Market 2023-2030 ($M) - Regional Industry Research
16.South America Cell Dissociation Market, By End User Market 2023-2030 ($M)
16.1 Pharmaceutical & Biotechnology Company Market 2023-2030 ($M) - Regional Industry Research
16.2 Research & Academic Institute Market 2023-2030 ($M) - Regional Industry Research
17.Europe Cell Dissociation Market, By Product Market 2023-2030 ($M)
17.1 Enzymatic Dissociation Product Market 2023-2030 ($M) - Regional Industry Research
17.1.1 Collagenase Market 2023-2030 ($M)
17.1.2 Trypsin Market 2023-2030 ($M)
17.1.3 Papain Market 2023-2030 ($M)
17.1.4 Elastase Market 2023-2030 ($M)
17.1.5 Dnase Market 2023-2030 ($M)
17.1.6 Hyaluronidase Market 2023-2030 ($M)
17.2 Non-Enzymatic Dissociation Product Market 2023-2030 ($M) - Regional Industry Research
17.3 Instrument & Accessory Market 2023-2030 ($M) - Regional Industry Research
18.Europe Cell Dissociation Market, By Tissue Market 2023-2030 ($M)
18.1 Connective Tissue Market 2023-2030 ($M) - Regional Industry Research
18.2 Epithelial Tissue Market 2023-2030 ($M) - Regional Industry Research
19.Europe Cell Dissociation Market, By Type Market 2023-2030 ($M)
19.1 Tissue Dissociation Market 2023-2030 ($M) - Regional Industry Research
19.2 Cell Detachment Market 2023-2030 ($M) - Regional Industry Research
20.Europe Cell Dissociation Market, By End User Market 2023-2030 ($M)
20.1 Pharmaceutical & Biotechnology Company Market 2023-2030 ($M) - Regional Industry Research
20.2 Research & Academic Institute Market 2023-2030 ($M) - Regional Industry Research
21.APAC Cell Dissociation Market, By Product Market 2023-2030 ($M)
21.1 Enzymatic Dissociation Product Market 2023-2030 ($M) - Regional Industry Research
21.1.1 Collagenase Market 2023-2030 ($M)
21.1.2 Trypsin Market 2023-2030 ($M)
21.1.3 Papain Market 2023-2030 ($M)
21.1.4 Elastase Market 2023-2030 ($M)
21.1.5 Dnase Market 2023-2030 ($M)
21.1.6 Hyaluronidase Market 2023-2030 ($M)
21.2 Non-Enzymatic Dissociation Product Market 2023-2030 ($M) - Regional Industry Research
21.3 Instrument & Accessory Market 2023-2030 ($M) - Regional Industry Research
22.APAC Cell Dissociation Market, By Tissue Market 2023-2030 ($M)
22.1 Connective Tissue Market 2023-2030 ($M) - Regional Industry Research
22.2 Epithelial Tissue Market 2023-2030 ($M) - Regional Industry Research
23.APAC Cell Dissociation Market, By Type Market 2023-2030 ($M)
23.1 Tissue Dissociation Market 2023-2030 ($M) - Regional Industry Research
23.2 Cell Detachment Market 2023-2030 ($M) - Regional Industry Research
24.APAC Cell Dissociation Market, By End User Market 2023-2030 ($M)
24.1 Pharmaceutical & Biotechnology Company Market 2023-2030 ($M) - Regional Industry Research
24.2 Research & Academic Institute Market 2023-2030 ($M) - Regional Industry Research
25.MENA Cell Dissociation Market, By Product Market 2023-2030 ($M)
25.1 Enzymatic Dissociation Product Market 2023-2030 ($M) - Regional Industry Research
25.1.1 Collagenase Market 2023-2030 ($M)
25.1.2 Trypsin Market 2023-2030 ($M)
25.1.3 Papain Market 2023-2030 ($M)
25.1.4 Elastase Market 2023-2030 ($M)
25.1.5 Dnase Market 2023-2030 ($M)
25.1.6 Hyaluronidase Market 2023-2030 ($M)
25.2 Non-Enzymatic Dissociation Product Market 2023-2030 ($M) - Regional Industry Research
25.3 Instrument & Accessory Market 2023-2030 ($M) - Regional Industry Research
26.MENA Cell Dissociation Market, By Tissue Market 2023-2030 ($M)
26.1 Connective Tissue Market 2023-2030 ($M) - Regional Industry Research
26.2 Epithelial Tissue Market 2023-2030 ($M) - Regional Industry Research
27.MENA Cell Dissociation Market, By Type Market 2023-2030 ($M)
27.1 Tissue Dissociation Market 2023-2030 ($M) - Regional Industry Research
27.2 Cell Detachment Market 2023-2030 ($M) - Regional Industry Research
28.MENA Cell Dissociation Market, By End User Market 2023-2030 ($M)
28.1 Pharmaceutical & Biotechnology Company Market 2023-2030 ($M) - Regional Industry Research
28.2 Research & Academic Institute Market 2023-2030 ($M) - Regional Industry Research
LIST OF FIGURES
1.US Cell Dissociation Market Revenue, 2023-2030 ($M)
2.Canada Cell Dissociation Market Revenue, 2023-2030 ($M)
3.Mexico Cell Dissociation Market Revenue, 2023-2030 ($M)
4.Brazil Cell Dissociation Market Revenue, 2023-2030 ($M)
5.Argentina Cell Dissociation Market Revenue, 2023-2030 ($M)
6.Peru Cell Dissociation Market Revenue, 2023-2030 ($M)
7.Colombia Cell Dissociation Market Revenue, 2023-2030 ($M)
8.Chile Cell Dissociation Market Revenue, 2023-2030 ($M)
9.Rest of South America Cell Dissociation Market Revenue, 2023-2030 ($M)
10.UK Cell Dissociation Market Revenue, 2023-2030 ($M)
11.Germany Cell Dissociation Market Revenue, 2023-2030 ($M)
12.France Cell Dissociation Market Revenue, 2023-2030 ($M)
13.Italy Cell Dissociation Market Revenue, 2023-2030 ($M)
14.Spain Cell Dissociation Market Revenue, 2023-2030 ($M)
15.Rest of Europe Cell Dissociation Market Revenue, 2023-2030 ($M)
16.China Cell Dissociation Market Revenue, 2023-2030 ($M)
17.India Cell Dissociation Market Revenue, 2023-2030 ($M)
18.Japan Cell Dissociation Market Revenue, 2023-2030 ($M)
19.South Korea Cell Dissociation Market Revenue, 2023-2030 ($M)
20.South Africa Cell Dissociation Market Revenue, 2023-2030 ($M)
21.North America Cell Dissociation By Application
22.South America Cell Dissociation By Application
23.Europe Cell Dissociation By Application
24.APAC Cell Dissociation By Application
25.MENA Cell Dissociation By Application
26.Bd, Sales /Revenue, 2015-2018 ($Mn/$Bn)
27.Thermo Fisher Scientific, Sales /Revenue, 2015-2018 ($Mn/$Bn)
28.F Hoffmann-La Roche Ltd, Sales /Revenue, 2015-2018 ($Mn/$Bn)
29.Ge Healthcare, Sales /Revenue, 2015-2018 ($Mn/$Bn)
30.Merck Kgaa, Sales /Revenue, 2015-2018 ($Mn/$Bn)
31.Atcc, Sales /Revenue, 2015-2018 ($Mn/$Bn)
32.Himedia Laboratory, Sales /Revenue, 2015-2018 ($Mn/$Bn)
33.Pan-Biotech, Sales /Revenue, 2015-2018 ($Mn/$Bn)
34.Miltenyi Biotec, Sales /Revenue, 2015-2018 ($Mn/$Bn)
35.Stemcell Technology, Sales /Revenue, 2015-2018 ($Mn/$Bn)
The Cell Dissociation Market is projected to grow at 16.3% CAGR during the forecast period 2024-2030.
The Cell Dissociation Market size is estimated to be $0.6 billion in 2023 and is projected to reach $1.7 billion by 2030
The leading players in the Cell Dissociation Market are Thermo Fisher Scientific, Corning Incorporated, BD, F Hoffmann-La Roche Ltd, GE Healthcare and Others
The growing use of single-cell RNA sequencing (scRNA-seq) techniques and use of AI are some of the major Cell Dissociation Market trends in the industry which will create growth opportunities for the market during the forecast period.
The are the driving factors of the market are growing demand for cell therapy, increasing investment in cell-based research & growth of pharmaceutical & biotechnological industries.